E: This group of substances has properties that give rise to concern besides the criteria for identification as “hazardous” e. g. according to CLP and should be used with caution. Once released to the environment they can pose a risk to the environment or human health even without having any yet identified adverse
effects on the environment or on human health via the environment.
Further measures are necessary:
• For operators: substitution, release minimisation up to prevention of emission, safe handling, check if substance belongs to substance group of concern,
e.g. PFAS, check information on ECHA website for assessment of chemicals universe
• For branch associations: give advice to installation operators, conduct research for substitution, …
• For TWG: derive BATs for BREFs, make sure that actual state of knowledge is reflected in BREFs at any time